Synthesis primarily takes place in the kidney and liver, with creatine then being transported to the muscles via the blood. After a year, dieters dropped 3. Mini Reviews in Medicinal Chemistry. For Mark Mincolla , Ph. If you've been noticing excess facial hair, period irregularities, acne, and you're obese, your doc may consider Polycystic Ovary Syndrome. As with most supplements, each person has their own genetic "preset" amount of creatine they can hold.
Dieting sucks. It tends to lead to cravings… and hunger. This generally causes people to give up on their diet and gain the weight back. For this reason, most conventional weight loss methods have a terrible success rate. Very few people succeed in the long run.